Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia
نویسندگان
چکیده
منابع مشابه
Bone turnover and hormonal perturbations in patients with fibromyalgia.
OBJECTIVE Studies of bone turnover in fibromyalgia (FM) have, to date, shown conflicting results. Although most patients with FM are women, only a few investigations have paid attention to the changes of sex hormones in FM. Moreover, FM is often viewed as a stress related disorder, and abnormalities of the hypothalamic-pituitary-adrenal (HPA) axis have been found in FM. The aim of the study was...
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A large body of data from a number of different laboratories worldwide has demonstrated a general tendency for reduced adrenocortical responsiveness in CFS. It is still not clear if this is secondary to CNS abnormalities leading to decreased activity of CRH- or AVP-producing hypothalamic neurons. Primary hypofunction of the CRH neurons has been described on the basis of genetic and environmenta...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1994
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780371105